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      4. WAMSI Node 5.4 - (PhD) Quorum quenching compounds from marine bacteria

      WAMSI Node 5.4 - (PhD) Quorum quenching compounds from marine bacteria

      Antibiotic resistance is of enormous concern in disease control and is one of the factors driving the search for new strategies for controlling bacterial growth. Quorum sensing (QS) is a bacterial communication process that allows control of gene expression in relation to cell density. Bacterial activities under QS control include the production of pigments and toxins, bioluminescence, swarming motility and biofilm formation. Quorum quenching (QQ) compounds inhibit the QS process, with the potential to control detrimental bacterial activities. QQ compounds have been isolated from several plants, algae, fungi and several bacteria. The aim of the project was to isolate and characterise QQ compounds from marine bacteria and investigating the mechanism by which the compound interferes with quorum sensing.

      Objectives of project were:

      (i) to purify and identify quorum quenching compounds (QQCs) from marine invertebrates and bacteria; (ii) to assess the diversity of quorum quenching effects and mechanisms of action amongst QQCs. (iii) to investigate ecological aspects of the formation and activity of QQCs (iv) to assess potential applications of QQCs.

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      • open PhD Thesis - Jamie Summerfield PDF

        Jamie Summerfield PhD (UWA) resulting from...

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      Activity Stream RDF JSON
      western-australian-marine-science-institution
      Key Information
      Published by
      Western Australian Marine Science Institution
      Information classification
      -
      Data theme
      Science
      Data last updated
      21-11-2017
      Update frequency
      -
      Data custodian
      Sutton, David, Associate Professor
      Dataset contact
      Maintainer Not Specified
      Website
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      First published
      -
      Metadata last updated
      20-05-2021
      Data source
      http://catalogue.aodn.org.au/geonetwork/srv/eng/metadata.show?uuid=c424f38e-457a-4213-9a55-26dbecee50d0
      Temporal coverage
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      Geospatial theme
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      Geospatial source projection
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      Spatial coverage

      Dataset extent

      Base map and data from OpenStreetMap and OpenStreetMap Foundation
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      Acknowledgement

      The Government of Western Australia respectfully acknowledges the traditional owners of country throughout Western Australia and pays its respects to Elders past, present and emerging.

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